well, id have to disagree. early machines used non-detergent oils, not because that was best but because detergent oils hadnt been invented. and single-grade oils were specified because thats all there was, not because multi-grade oils were inferior.
so far as i know the only functional difference between conventional and synthetic oils is in lubricity. i have an old truck that gets 11.6mpg on conventional multigrade oil. on synthetic, it gets 13.6, a significant improvement.
the increased lubricity isnt an advantage if we re running in a motor honed with traditionally coarse 180-grit finishes, and is said to slow
break-in and possibly burnish the bores. but after tbe rings are bedded i dont know of any disadvantages to synthetic oils besides the cost.
im not talking about oils with polymer friction modifiers and how they dont work with a wet clutch-- thats taken care of by selecting oils without those adfitives. likewise for the zinc additives needed for flat tappets. but for the motor itself, absent the primary chaincase, i wouldnt hesitate to use a synthetic unless i knew more than i know now.